5-Hydroxy-6,7-dimethoxylflavone
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1575 | Check With Us |
| 200mg | $2360 | Check With Us |
| 500mg | $3980 | Check With Us |
: Cat #: V34272 CAS #: 740-33-0 Purity ≥ 99%
Description: 5-Hydroxy-6,7-dimethoxylflavone is natural product of the flavonoid class.
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| Molecular Weight (MW) | 298.29 |
|---|---|
| Molecular Formula | C17H14O5 |
| CAS No. | 740-33-0 |
| Synonyms | 5-Hydroxy-6,7-dimethoxylflavone |
| Protocol | In Vitro | Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3524 mL | 16.7622 mL | 33.5244 mL | 67.0488 mL |
| 5mM | 0.6705 mL | 3.3524 mL | 6.7049 mL | 13.4098 mL |
| 10mM | 0.3352 mL | 1.6762 mL | 3.3524 mL | 6.7049 mL |
| 20mM | 0.1676 mL | 0.8381 mL | 1.6762 mL | 3.3524 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.