4-IBP

This product is for research use only, not for human use. We do not sell to patients.

4-IBP
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1025Check With Us
500mg$1588Check With Us
1g$2382Check With Us

Cat #: V3950 CAS #: 155798-08-6 Purity ≥ 98%

Description: 4-IBP is a novel and selective σ1 (sigma1) agonist with high affinity for the σ1 receptor with Ki of 1.7 nM and a moderate affinity for the σ2 receptor (Ki = 25.2 nM).

References: Mégalizzi V, et al. 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. Neoplasia. 2

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Product Promise

Promise
Molecular Weight (MW)420.29
Molecular FormulaC₁₉H₂₁IN₂O
CAS No.155798-08-6
Storage-20℃ for 3 years in powder formrrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mMrrr
Water: N/Arrr
Ethanol: N/A
SMILES CodeO=C(NC1CCN(CC2=CC=CC=C2)CC1)C3=CC=C(I)C=C3
Synonyms4-IBP; 4 IBP; 4IBP
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3793 mL11.8965 mL23.7931 mL47.5862 mL
5mM0.4759 mL2.3793 mL4.7586 mL9.5172 mL
10mM0.2379 mL1.1897 mL2.3793 mL4.7586 mL
20mM0.1190 mL0.5948 mL1.1897 mL2.3793 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.