4-Aminobutyric acid

This product is for research use only, not for human use. We do not sell to patients.

4-Aminobutyric acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$380Check With Us
50g$650Check With Us
100g$975Check With Us

Cat #: V2709 CAS #: 56-12-2 Purity ≥ 98%

Description: Gamma-Aminobutyric Acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid) is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity.

References: Chen S, et al. Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets. Food Funct. 2019 Jan 2.

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Molecular Weight (MW)103.12
Molecular FormulaC4H9NO2
CAS No.56-12-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLrr
Water: 20 mg/mL (193.9 mM)rr
Ethanol: <1 mg/mL
SMILES CodeO=C(O)CCCN
Synonyms4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid; Aminalon; DF 468; DF468; DF-468; Mielogen; Mielomade; Gamma-aminobutyric acid
ProtocolIn Vitroγ-Aminobutyric acid (30 μM) depolarizes cortical progenitor cells (E16 cells), results an inward current in ventricular zone (VZ) cells, and induces DNA synthesis inhibition, with half-maximal response concentration of 5 μM
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM9.6974 mL48.4872 mL96.9744 mL193.9488 mL
5mM1.9395 mL9.6974 mL19.3949 mL38.7898 mL
10mM0.9697 mL4.8487 mL9.6974 mL19.3949 mL
20mM0.4849 mL2.4244 mL4.8487 mL9.6974 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.