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3-Sialyllactose sodium

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3-Sialyllactose sodium
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Size Price Stock
1g$600Check With Us
2g$900Check With Us
5g$1520Check With Us

Cat #: V41229 CAS #: 128596-80-5 Purity ≥ 99%

Description: 3-Sialyllactose sodium salt is a biochemical compound used to differentiate and characterize binding domains of viruses.

References: Jeon J, et al. 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis. J Cell Mol Med. 2018 Jan;22(1):57-66.

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Molecular Weight (MW)655.53
Molecular FormulaC23H38NNaO19
CAS No.128596-80-5
ProtocolIn Vitro3'-Sialyllactose sodium (0-250 μM; 24 h) activates the expression of Sox9 and inhibits NF-κB activation in chondrocytes. 3'-Sialyllactose sodium (0-250 μM; 24-36 h) promotes and restores Col2a1 synthesis and accumulates extracellular sulphated proteoglycan, and inhibits the effect of inflammatory cytokines.
In Vivo3'-Sialyllactose sodium (10-100 mg/kg; p.o. three times a week for 6 weeks) protects mice against cartilage destruction from osteoarthritis.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5255 mL7.6274 mL15.2548 mL30.5097 mL
5mM0.3051 mL1.5255 mL3.0510 mL6.1019 mL
10mM0.1525 mL0.7627 mL1.5255 mL3.0510 mL
20mM0.0763 mL0.3814 mL0.7627 mL1.5255 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.