2′,3′-cGAMP sodium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $6075 | To Be Confirmed |
| 200mg | $9110 | To Be Confirmed |
| 500mg | $15375 | To Be Confirmed |
: Cat #: V37554 CAS #: N/A Purity ≥ 99%
Description: 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is an endogenous cGAMP molecule found in mammalian cells, it binds to STING with high affinity and is a potent inducer of interferon-β (IFNβ).
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 718.37 |
|---|---|
| Molecular Formula | C20H22N10Na2O13P2 |
| CAS No. | N/A |
| Synonyms | 2',3'-cGAMP sodium; 2'-3'-cyclic GMP-AMP sodium |
| Protocol | In Vitro | 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) contains two distinct phosphodiester linkages, one between 2′-OH of GMP and 5′-phosphate of AMP, and the other between 3′-OH of AMP and 5′-phosphate of GMP. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.3920 mL | 6.9602 mL | 13.9204 mL | 27.8408 mL |
| 5mM | 0.2784 mL | 1.3920 mL | 2.7841 mL | 5.5682 mL |
| 10mM | 0.1392 mL | 0.6960 mL | 1.3920 mL | 2.7841 mL |
| 20mM | 0.0696 mL | 0.3480 mL | 0.6960 mL | 1.3920 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.