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2-Hydroxyflutamide (Hydroxyniphtholide)

This product is for research use only, not for human use. We do not sell to patients.

2-Hydroxyflutamide (Hydroxyniphtholide)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$450Check With Us
500mg$700Check With Us
1g$1050Check With Us
email: [email protected]        [email protected]

Cat #: V9396 CAS #: 52806-53-8 Purity ≥ 98%

Description: 2-Hydroxyflutamide (Hydroxyniphtholide), a metabolite of flutamide, is an androgen receptor antagonist potentially for the treatment of prostate cancer.

References: Furr BJ, et, al. Casodex: preclinical studies and controversies. Ann N Y Acad Sci. 1995 Jun 12;761:79-96. 

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Molecular Weight (MW)292.21
Molecular FormulaC11H11F3N2O4
CAS No.52806-53-8
Synonyms2-HOF; 2HOF; 2 HOF
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4222 mL17.1110 mL34.2220 mL68.4439 mL
5mM0.6844 mL3.4222 mL6.8444 mL13.6888 mL
10mM0.3422 mL1.7111 mL3.4222 mL6.8444 mL
20mM0.1711 mL0.8555 mL1.7111 mL3.4222 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.