16alpha-Hydroxyprednisolone

This product is for research use only, not for human use. We do not sell to patients.

16alpha-Hydroxyprednisolone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$400To Be Confirmed
250mg$750To Be Confirmed
500mg$1125To Be Confirmed

Cat #: V9224 CAS #: 13951-70-7 Purity ≥ 99%

Description: 16alpha-Hydroxyprednisolone (Budesonide Impurity A) is a CYP3A-mediated metabolite and 22(R) epimer of budesonide which is a glucocorticoid.

References: Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40.

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Molecular Weight (MW)376.44
Molecular FormulaC21H28O6
CAS No.13951-70-7
SMILES Code O=C1C=C[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C)[C@](C(CO)=O)(O)[C@H](O)C[C@@]4([H])[C@]3([H])CCC2=C1
Synonyms16alpha-Hydroxyprednisolone; OH-PRED; OH PRED; 16alpha Hydroxyprednisolone;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6565 mL13.2823 mL26.5647 mL53.1293 mL
5mM0.5313 mL2.6565 mL5.3129 mL10.6259 mL
10mM0.2656 mL1.3282 mL2.6565 mL5.3129 mL
20mM0.1328 mL0.6641 mL1.3282 mL2.6565 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.