Zidebactam
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1550 | Check With Us |
| 200mg | $2325 | Check With Us |
| 500mg | $3920 | Check With Us |
: Cat #: V28484 CAS #: 1436861-97-0 Purity ≥ 99%
Description: Zidebactam (WCK-5107; WCK5107) is a potent β-lactamase inhibitor and also a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.
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| Molecular Weight (MW) | 391.40 |
|---|---|
| Molecular Formula | C13H21N5O7S |
| CAS No. | 1436861-97-0 |
| SMILES Code | O=C(NNC([C@@H]1CC[C@@H]2C[N@]1C(N2OS(=O)(O)=O)=O)=O)[C@@H]3CCCNC3 |
| Synonyms | Zidebactam; WCK-5107; WCK 5107; WCK5107 |
| Protocol | In Vitro | Zidebactam (WCK-5107) inhibits WT Enterobacteriaceae with a MIC50 of 0.25 mg/L. Zidebactam alone exhibits variable activity when tested against E. coli (MIC50/90 0.12/0.12 mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25 mg/L). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5549 mL | 12.7747 mL | 25.5493 mL | 51.0986 mL |
| 5mM | 0.5110 mL | 2.5549 mL | 5.1099 mL | 10.2197 mL |
| 10mM | 0.2555 mL | 1.2775 mL | 2.5549 mL | 5.1099 mL |
| 20mM | 0.1277 mL | 0.6387 mL | 1.2775 mL | 2.5549 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.