Z-VAD(OH)-FMK (Caspase Inhibitor VI)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1800 | Check With Us |
| 200mg | $2700 | Check With Us |
| 500mg | $4555 | Check With Us |
: Cat #: V0032 CAS #: 161401-82-7 Purity ≥ 98%
Description: Z-VAD-FMK (Caspase Inhibitor VI; Z-VAD(OH)-FMK) is a novel, potent and irreversible pan caspase inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 453.46 |
|---|---|
| Molecular Formula | C21H28FN3O7 |
| CAS No. | 161401-82-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 90 mg/mL (198.47 mM)r |
| Water:<1 mg/mL (slightly soluble or insoluble)r | |
| Ethanol: N/A | |
| SMILES Code | O=C(O)C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O |
| Synonyms | Z-VAD(OH)-FMK; Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2053 mL | 11.0263 mL | 22.0527 mL | 44.1053 mL |
| 5mM | 0.4411 mL | 2.2053 mL | 4.4105 mL | 8.8211 mL |
| 10mM | 0.2205 mL | 1.1026 mL | 2.2053 mL | 4.4105 mL |
| 20mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.2053 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.