YKL-5-124
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $700 | Check With Us |
| 100mg | $1200 | Check With Us |
| 200mg | $1800 | Check With Us |
: Cat #: V41716 CAS #: 1957203-01-8 Purity ≥ 99%
Description: YKL-5-124 (YKL-5124) is a novel, selective, and covalent CDK7 inhibitor (IC50=53.5 nM) with anticancer activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 515.61 |
|---|---|
| Molecular Formula | C28H33N7O3 |
| CAS No. | 1957203-01-8 |
| Protocol | In Vitro | YKL-5-124 (0-2000 nM; 72 hours; HAP1 cells) treatment causes a dose-dependent increase in G1- and G2/M-phase cells and a corresponding loss of S-phase cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9395 mL | 9.6973 mL | 19.3945 mL | 38.7890 mL |
| 5mM | 0.3879 mL | 1.9395 mL | 3.8789 mL | 7.7578 mL |
| 10mM | 0.1939 mL | 0.9697 mL | 1.9395 mL | 3.8789 mL |
| 20mM | 0.0970 mL | 0.4849 mL | 0.9697 mL | 1.9395 mL |
The molarity calculator equation
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The dilution calculator equation
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.