Y11

This product is for research use only, not for human use. We do not sell to patients.

Y11
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$850To Be Confirmed
200mg$1275To Be Confirmed
500mg$2150To Be Confirmed

Cat #: V28341 CAS #: 1086639-59-9 Purity ≥ 99%

Description: Y11 (Y-11) is a novel and potent small molecule inhibitor of FAK (focal adhesion kinase) with potential anticancer activity.

References: Golubovskaya VM, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem. 2008 Dec 11;51(23):7405-16. 

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Promise
Molecular Weight (MW)265.15
Molecular FormulaC8H17BrN4O
CAS No.1086639-59-9
SMILES CodeOCC[N+]12C[N@]3C[N@](C2)C[N@](C3)C1.[Br-]
SynonymsY11; Y-11; Y 11
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.7715 mL18.8573 mL37.7145 mL75.4290 mL
5mM0.7543 mL3.7715 mL7.5429 mL15.0858 mL
10mM0.3771 mL1.8857 mL3.7715 mL7.5429 mL
20mM0.1886 mL0.9429 mL1.8857 mL3.7715 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.