WS3
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1250 | Check With Us |
| 1g | $1850 | Check With Us |
| 5g | $4680 | Check With Us |
: Cat #: V0758 CAS #: 1421227-52-2 Purity ≥ 98%
Description: WS-3 (WS3; WS 3) is a novel and potent small molecule modulatior of Erb3 binding protein-1 (EBP1) and the IκB (IkappaB) kinase with important biological activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 569.58 |
|---|---|
| Molecular Formula | C28H30F3N7O3 |
| CAS No. | 1421227-52-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (175.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 80 mg/mL warmed (140.5 mM) | |
| SMILES Code | CN1CCN(CC2=CC=C(NC(NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=N4)C=C3)=O)C=C2C(F)(F)F)CC1 |
| Synonyms | WS-3; WS 3; WS3; |
| Protocol | In Vitro | WS3 induces pancreatic R7T1 β cell proliferation in dose response, with an EC50 value of 0.28 μM. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7557 mL | 8.7784 mL | 17.5568 mL | 35.1136 mL |
| 5mM | 0.3511 mL | 1.7557 mL | 3.5114 mL | 7.0227 mL |
| 10mM | 0.1756 mL | 0.8778 mL | 1.7557 mL | 3.5114 mL |
| 20mM | 0.0878 mL | 0.4389 mL | 0.8778 mL | 1.7557 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.