Wilforlide A (Regelide; Abruslactone A)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $1240 | Check With Us |
500mg | $1750 | Check With Us |
1g | $2625 | Check With Us |
Cat #: V5097 CAS #: 84104-71-2 Purity ≥ 99%
Description: Wilforlide A (also known as Regelide and Abruslactone A) is a natural product isolated from the ethanolic extract of tripterygium wilfordii.
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Molecular Weight (MW) | 454.68 |
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Molecular Formula | C30H46O3 |
CAS No. | 84104-71-2 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | O=C1[C@@](C2)(C)C[C@]3([H])[C@](CC[C@@]4(C)[C@]5(C)CC[C@@]6([H])C(C)(C)[C@@H](O)CC[C@]6(C)[C@@]5([H])CC=C43)(C)[C@@]2([H])O1 |
Synonyms | Abruslactone A; Wilforlide A; Regelide; |
Protocol | In Vivo | Wilforlide A (30-150 μg/kg) markedly inhibits rat granulation induced by tampon. Wilforlide A (60-300 μg/kg) markedly inhibits mice auricular swelling induced by dimethylbenzene in ICR mice. Wilforlide A exhibits inhibition rates with 50.9% and 12.29% for high dose and low dose Wilforlide A, resepectively. |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.1993 mL | 10.9967 mL | 21.9935 mL | 43.9870 mL |
5mM | 0.4399 mL | 2.1993 mL | 4.3987 mL | 8.7974 mL |
10mM | 0.2199 mL | 1.0997 mL | 2.1993 mL | 4.3987 mL |
20mM | 0.1100 mL | 0.5498 mL | 1.0997 mL | 2.1993 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.