Home > Signaling Pathways>Anti-infection>Influenza Virus>VX-787 (Pimodivir)
VX-787 (Pimodivir)

This product is for research use only, not for human use. We do not sell to patients.

VX-787 (Pimodivir)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250To Be Confirmed
500mg$1999To Be Confirmed
1g$2995To Be Confirmed
email: [email protected]        [email protected]

Cat #: V28136 CAS #: 1629869-44-8 Purity ≥ 99%

Description: Pimodivir (formerly VX787; JNJ872; VRT-0928787; VX-787; JNJ-872) is a novel and orally bioavailable inhibitor of influenza virus replication by blocking the PB2 cap-snatching activity of the influenza viral polymerase complex.

References: Smee DF, et al. Activities of JNJ63623872 and GS 4071 against influenza A H1N1pdm and H3N2 virus infections in mice. Antiviral Res. 2016 Dec;136:45-50.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)399.39
Molecular FormulaC20H19F2N5O2
CAS No.1629869-44-8
SMILES CodeO=C([C@H]1C(CC2)CCC2[C@@H]1NC3=NC(C4=CNC5=NC=C(F)C=C54)=NC=C3F)O
SynonymsJNJ-63623872; JNJ63623872; JNJ 63623872; JNJ-872; JNJ 872; JNJ872; VRT-0928787; VRT 0928787; VRT0928787; pimodivir; VX-787; VX 787; VX787;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5038 mL12.5191 mL25.0382 mL50.0764 mL
5mM0.5008 mL2.5038 mL5.0076 mL10.0153 mL
10mM0.2504 mL1.2519 mL2.5038 mL5.0076 mL
20mM0.1252 mL0.6260 mL1.2519 mL2.5038 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.