Visomitin (SKQ-1)

This product is for research use only, not for human use. We do not sell to patients.

Visomitin (SKQ-1)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$780Check With Us
1g$1200Check With Us
5g$3035Check With Us

Cat #: V19746 CAS #: 934826-68-3 Purity ≥ 98%

Description: Visomitin (SKQ1; plastoquinonyl decyltriphenyl phosphonium; PDTP) is a higly potent mitochondria-targeted antioxidant and topical cardiolipin peroxidation inhibitor with excellent mitochondrion membrane penetrating ability.

References: Bazhin AV, et al. The novel mitochondria-targeted antioxidant SkQ1 modulates angiogenesis and inflammatory micromilieu in a murine orthotopic model of pancreatic cancer. Int J Cancer. 2016 Jul 1;139(1):130-9.

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Product Promise

Promise
Molecular Weight (MW)617.60
Molecular FormulaC36H42BrO2P
CAS No.934826-68-3
SMILES CodeO=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4)C(C)=C(C)C4=O.[Br-]
SynonymsSKQ1; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide;Visomitin
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6192 mL8.0959 mL16.1917 mL32.3834 mL
5mM0.3238 mL1.6192 mL3.2383 mL6.4767 mL
10mM0.1619 mL0.8096 mL1.6192 mL3.2383 mL
20mM0.0810 mL0.4048 mL0.8096 mL1.6192 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.