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Varenicline Tartrate (CP 526555-18)

This product is for research use only, not for human use. We do not sell to patients.

Varenicline Tartrate (CP 526555-18)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$509Check With Us
250mg$879Check With Us
500mg$1319Check With Us

Cat #: V1203 CAS #: 375815-87-5 Purity ≥ 98%

Description: Varenicline Tartrate (CP-526555 18; CP 526555 18; Chantix; Champix), the tartrate salt of varenicline, is a potent partial agonist of nicotinic AChR (acetylcholine receptor) used for smoke-cessation and nicotine addiction.

References: Krebs P, Sherman SE. Review: Varenicline for tobacco cessation does not increase CV serious adverse events. Ann Intern Med. 2012 Aug 21;157(4):JC2-2.

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Product Promise

Promise
Molecular Weight (MW)361.35
Molecular FormulaC13H13N3·C4H6O6
CAS No.375815-87-5
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLrr
Water: 72 mg/mL (199.3 mM)rr
Ethanol: <1 mg/mL
SMILES CodeC1[C@@H]2CNC[C@H]1C3=CC4=NC=CN=C4C=C23.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
SynonymsCP 526555-18; CP52655518; Varenicline tartrate; CP-526555 18; CP 526555 18; Chantix; Champix
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7674 mL13.8370 mL27.6740 mL55.3480 mL
5mM0.5535 mL2.7674 mL5.5348 mL11.0696 mL
10mM0.2767 mL1.3837 mL2.7674 mL5.5348 mL
20mM0.1384 mL0.6919 mL1.3837 mL2.7674 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.