VAPREOTIDE ACETATE

This product is for research use only, not for human use. We do not sell to patients.

VAPREOTIDE ACETATE
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1350Check With Us
250mg$2380Check With Us
500mg$3570Check With Us

Cat #: V4358 CAS #: 849479-74-9 Purity ≥ 98%

Description: Vapreotide acetate (trade name: Sanvar) is a synthetic somatostatin analog and a NK1R antagonist with an IC50 of 330 nM.

References: Spitsin S, et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20(5):247-55.

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Product Promise

Promise
Molecular Weight (MW)1191.39
Molecular FormulaC57H70N12O9S2.xC2H4O2
CAS No.849479-74-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VitroVapreotide attenuates the Substance P (SP)-triggered intracellular calcium increases and NF-κB activation in a dose-dependent manner. Vapreotide also inhibits SP-induced IL-8 and MCP-1 production in HEK293-NK1R and U373MG cell lines. Vapreotide inhibits HIV-1 infection of human MDM in vitro, an effect that is reversible by SP pretreatment
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.8394 mL4.1968 mL8.3936 mL16.7871 mL
5mM0.1679 mL0.8394 mL1.6787 mL3.3574 mL
10mM0.0839 mL0.4197 mL0.8394 mL1.6787 mL
20mM0.0420 mL0.2098 mL0.4197 mL0.8394 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.