(+)-Usniacin

This product is for research use only, not for human use. We do not sell to patients.

(+)-Usniacin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$340Check With Us
5g$550Check With Us
10g$825Check With Us

Cat #: V2177 CAS #: 7562-61-0 Purity ≥ 98%

Description: (+)-Usniacin, [(+)-Usnic acid] is a natually occuring compound isolated from lichens, which binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity.

References: Ebrahim HY, et al. Usnic Acid Benzylidene Analogues as Potent Mechanistic Target of Rapamycin Inhibitors for the Control of Breast Malignancies. J Nat Prod. 2017 Apr 28;80(4):932-952.

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Product Promise

Promise
Molecular Weight (MW)344.32
Molecular FormulaC18H16O7
CAS No.7562-61-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 4 mg/mL warmed (11.61 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeC[C@](C(O1)=CC2=O)(C(O)=C2C(C)=O)C3=C1C(C(C)=O)=C(O)C(C)=C3O
Synonyms(+)-Usnic acid
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9043 mL14.5214 mL29.0428 mL58.0855 mL
5mM0.5809 mL2.9043 mL5.8086 mL11.6171 mL
10mM0.2904 mL1.4521 mL2.9043 mL5.8086 mL
20mM0.1452 mL0.7261 mL1.4521 mL2.9043 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.