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USL311

This product is for research use only, not for human use. We do not sell to patients.

USL311
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$750Check With Us
100mg$1125Check With Us
200mg$1685Check With Us
email: [email protected]        [email protected]

Cat #: V27884 CAS #: 1373268-67-7 Purity ≥ 99%

Description: USL311 is a novel, selective and potent CXCR4 receptor antagonist with anticancer activity by disrupting the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4, which prevents CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells.

References: Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790.

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Molecular Weight (MW)422.57
Molecular FormulaC24H34N6O
CAS No.1373268-67-7
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3665 mL11.8324 mL23.6647 mL47.3294 mL
5mM0.4733 mL2.3665 mL4.7329 mL9.4659 mL
10mM0.2366 mL1.1832 mL2.3665 mL4.7329 mL
20mM0.1183 mL0.5916 mL1.1832 mL2.3665 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.