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| Size | Price | Stock |
|---|---|---|
| 25mg | $120 | 3-6 Days |
| 50mg | $210 | 3-6 Days |
| 100mg | $320 | 3-6 Days |
| 250mg | $430 | 3-6 Days |
: Cat #: V0637 CAS #: 1493764-08-1 Purity ≥ 99%
Description: UNC2881 (UNC-2881) is a novel, potent and specific Mer tyrosine kinase inhibitor with potential utility for prevention and treatment of pathologic thrombosis. It exhibits 83- and 58-fold higher selectivity over Tyro3 and Axl, respectively, and inhibits Mer with an IC50 of 4.3 nM. Since Mer kinase controls the second stage of platelet activation, using Mer inhibitors to prevent thrombosis with a lower risk of bleeding than existing treatments presents an opportunity.
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| Molecular Weight (MW) | 463.58 |
|---|---|
| Molecular Formula | C25H33N7O2 |
| CAS No. | 1493764-08-1 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | UNC-2881; UNC 2881; UNC2881 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1571 mL | 10.7856 mL | 21.5712 mL | 43.1425 mL |
| 5mM | 0.4314 mL | 2.1571 mL | 4.3142 mL | 8.6285 mL |
| 10mM | 0.2157 mL | 1.0786 mL | 2.1571 mL | 4.3142 mL |
| 20mM | 0.1079 mL | 0.5393 mL | 1.0786 mL | 2.1571 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.