Ubenimex HCl

This product is for research use only, not for human use. We do not sell to patients.

Ubenimex HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$750Check With Us
1g$1250Check With Us
5g$3165Check With Us

Cat #: V27773 CAS #: 65391-42-6 Purity ≥ 99%

Description: Ubenimex HCl (Bestatin hydrochloride) is a novel and potent CD13 inhibitor or Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor with the potential to be used for cancer treatment.

References: Hossain A, et al. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 Aug;149:100-6

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Molecular Weight (MW)344.83
Molecular FormulaC16H25ClN2O4
CAS No.65391-42-6
SMILES CodeCC(C)C[C@H](NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O)C(O)=O.[H]Cl
SynonymsBestatin HCl; NSC 265489, NSC265489, NSC-265489, Ubenimex, NK 421, NK-421, NK421, Bestatin,
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9000 mL14.4999 mL28.9998 mL57.9996 mL
5mM0.5800 mL2.9000 mL5.8000 mL11.5999 mL
10mM0.2900 mL1.4500 mL2.9000 mL5.8000 mL
20mM0.1450 mL0.7250 mL1.4500 mL2.9000 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.