U0126-EtOH

This product is for research use only, not for human use. We do not sell to patients.

U0126-EtOH
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$903-6 Days
50mg$1403-6 Days
100mg$2303-6 Days
250mg$4103-6 Days
500mg$6403-6 Days
1g$8803-6 Days
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V0447 CAS #: 1173097-76-1 Purity ≥ 99%

Description: U0126-EtOH is a novel, selective and non-ATP competitive MEK1/2 inhibitor with potential anticviral activity. In cell-free assays, it inhibits MEK1/2 with IC50 values of 0.07 μM/0.06 μM.

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Molecular Weight (MW)426.56
Molecular FormulaC18H16N6S2.C2H6O
CAS No.1173097-76-1
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsU0126; U-0126-EtOH; U0126 EtOH; U 0126; U-0126; U0126-EtOH; U 0126-EtOH; U 0126 EtOH; U0126 Ethanol; U0126.EtOH; (2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)succinonitrile compound with ethanol (1:1); (2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile;ethanol; 2,3-Bis(amino((2-aminophenyl)thio)methylene)succinonitrile compound with ethanol (1:1); U0126 ethanolate; .U-0126 EtOH
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3443 mL11.7217 mL23.4434 mL46.8867 mL
5mM0.4689 mL2.3443 mL4.6887 mL9.3773 mL
10mM0.2344 mL1.1722 mL2.3443 mL4.6887 mL
20mM0.1172 mL0.5861 mL1.1722 mL2.3443 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.