Tyrphostin AG 957

This product is for research use only, not for human use. We do not sell to patients.

Tyrphostin AG 957
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
200mg$1125Check With Us
500mg$1900Check With Us

Cat #: V10992 CAS #: 140674-76-6 Purity ≥ 99%

Description: AG957 (Tyrphostin AG-)957 is a novel and potent TKI-tyrosine kinase inhibitor, which selectively inhibits human p210 tyrosine kinase activity.

References: G Kaur, et al. Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia. Anticancer Drugs. 1994 Apr;5(2):213-22.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)273.28
Molecular FormulaC15H15NO4
CAS No.140674-76-6
SMILES Code OC1=C(CNC2=CC=C(C(OC)=O)C=C2)C=C(O)C=C1
SynonymsTyrphostin AG 957
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.6593 mL18.2963 mL36.5925 mL73.1850 mL
5mM0.7319 mL3.6593 mL7.3185 mL14.6370 mL
10mM0.3659 mL1.8296 mL3.6593 mL7.3185 mL
20mM0.1830 mL0.9148 mL1.8296 mL3.6593 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.