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Tyrphostin 9 (AG17; Malonoben)

This product is for research use only, not for human use. We do not sell to patients.

Tyrphostin 9 (AG17; Malonoben)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$375Check With Us
1g$650Check With Us
5g$1645Check With Us

Cat #: V0564 CAS #: 10537-47-0 Purity ≥ 98%

Description: Tyrphostin-9 (also named as Malonoben; SF-6847; RG-50872; AG-17; GCP-5126; NSC-242557) is a novel and potent epidermal growth factor receptor (EGFR) inhibitor with potential anticancer activity.

References: Park SJ, Park YJ, Shin JH, et al. A receptor tyrosine kinase inhibitor, Tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation. Biochem Biophys Res Commun. 2011 May 13;408(3):465-70.

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Product Promise

Promise
Molecular Weight (MW)282.38
Molecular FormulaC18H22N2O
CAS No.10537-47-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 56 mg/mL (198.3 mM)r
Water: <1 mg/mLr
Ethanol: 56 mg/mL (198.3 mM)
SMILES CodeN#C/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
SynonymsRG50872; SF-6847; RG-50872; AG-17; GCP-5126; NSC-242557; SF6847; RG50872; AG17; GCP5126; NSC242557; SF 6847; RG 50872; AG 17; GCP 5126; NSC 242557; Tyrphostin-9; Tyrphostin 9; Tyrphostin9; Malonoben; Tyrphostin AG17;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5413 mL17.7066 mL35.4133 mL70.8265 mL
5mM0.7083 mL3.5413 mL7.0827 mL14.1653 mL
10mM0.3541 mL1.7707 mL3.5413 mL7.0827 mL
20mM0.1771 mL0.8853 mL1.7707 mL3.5413 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.