Tubercidin (7-Deazaadenosine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $780 | In Stock |
| 1g | $1280 | In Stock |
| 5g | $3456 | In Stock |
: Cat #: V16926 CAS #: 69-33-0 Purity ≥ 98%
Description: Tubercidin (7-Deazaadenosine), an antibiotic isolated from Streptomyces tubercidicus, is a DNA/RNA Synthesis inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 266.25 |
|---|---|
| Molecular Formula | C11H14N4O4 |
| CAS No. | 69-33-0 |
| Protocol | In Vitro | Tubercidin (7-Deazaadenosine) (0-10 nM; 14 days) has a dose-dependent inhibitory effect on myeloid and erythroid human bone marrow progenitor cells, and the IC50s of tubercidin were 3.4 nM and 3.7 nM for CFU-GM and BFU-E, respectively |
|---|---|---|
| In Vivo | Tubercidin (7-Deazaadenosine) (intraperitoneal injection; 5 mg/kg; 10 days) in cooperation with NBMPR-P protects the mice from the lethality of tubercidin and allowed the repetition of the regimen for a second time with 100% survival |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.7559 mL | 18.7793 mL | 37.5587 mL | 75.1174 mL |
| 5mM | 0.7512 mL | 3.7559 mL | 7.5117 mL | 15.0235 mL |
| 10mM | 0.3756 mL | 1.8779 mL | 3.7559 mL | 7.5117 mL |
| 20mM | 0.1878 mL | 0.9390 mL | 1.8779 mL | 3.7559 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.