Tubastatin A TFA

This product is for research use only, not for human use. We do not sell to patients.

Tubastatin A TFA
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Size Price Stock
100mg$550Check With Us
250mg$990Check With Us
500mg$1485Check With Us

Cat #: V2404 CAS #: 1239262-52-2 Purity ≥ 99%

Description: Tubastatin A (TubA, AG-CR13900) TFA, the trifluoroacetic acid salt of TubA, is an inhibitor of HDAC6 with anticancer and anti-inflammatory activity.

References: Yan-Yang Gao, et al. The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma. Theranostics. 2021 Mar 4;11(10):4599-4615.

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Molecular Weight (MW)400.42
Molecular Formula400.42
CAS No.1239262-52-2
SMILES CodeCC1=CC(C2=CC=CC=C2)=CC(C(NNS(=O)(C3=CC(O)=CC=C3)=O)=O)=C1F
SynonymsWM 3835; WM3835; WM-3835;
ProtocolIn VitroWM-3835 (1-25 uM; 24-96 hours) inhibits pOS-1 cell viability in a concentration-dependent manner. WM-3835 (1-25 uM; 24-96 hours) inhibits pOS-1 cell viability in a concentration-dependent manner. WM-3835 (1-25 uM; 24-96 hours) inhibits pOS-1 cell viability in a concentration-dependent manner.
In VivoWM-3835 (1-25 uM; 24-96 hours) inhibits pOS-1 cell viability in a concentration-dependent manner.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4974 mL12.4869 mL24.9738 mL49.9476 mL
5mM0.4995 mL2.4974 mL4.9948 mL9.9895 mL
10mM0.2497 mL1.2487 mL2.4974 mL4.9948 mL
20mM0.1249 mL0.6243 mL1.2487 mL2.4974 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.