TTP 22
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $750 | Check With Us |
| 500mg | $1280 | Check With Us |
| 1g | $1920 | Check With Us |
: Cat #: V3398 CAS #: 329907-28-0 Purity ≥ 98%
Description: TTP 22 is a novel, selective and potent inhibitor of human protein kinase CK2 with an IC50 of 100 nM and a Ki of 40 nM.
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| Molecular Weight (MW) | 330.42 |
|---|---|
| Molecular Formula | C16H14N2O2S2 |
| CAS No. | 329907-28-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1 |
| Synonyms | TTP 22; TTP-22; TTP22 |
| Protocol | In Vitro | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0265 mL | 15.1323 mL | 30.2645 mL | 60.5290 mL |
| 5mM | 0.6053 mL | 3.0265 mL | 6.0529 mL | 12.1058 mL |
| 10mM | 0.3026 mL | 1.5132 mL | 3.0265 mL | 6.0529 mL |
| 20mM | 0.1513 mL | 0.7566 mL | 1.5132 mL | 3.0265 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.