Tretazicar (CB 1954)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $750 | To Be Confirmed |
| 1g | $1250 | To Be Confirmed |
| 5g | $3375 | To Be Confirmed |
: Cat #: V10141 CAS #: 21919-05-1 Purity ≥ 98%
Description: Tretazicar (CB-1954; CB1954), a dinitrobenzamide analog and prodrug, is a potent and highly selective DNA alkylating agent that generates highly cytotoxic interstrand crosslinks in DNA.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 252.18 |
|---|---|
| Molecular Formula | C9H8N4O5 |
| CAS No. | 21919-05-1 |
| Protocol | In Vitro | Tretazicar (CB 1954) (0.1-1000 μM; 3 days) has sensitivity for retrovirally transduced AB22 (AB22-nr) cells with an IC50 of 3 μM |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9654 mL | 19.8271 mL | 39.6542 mL | 79.3084 mL |
| 5mM | 0.7931 mL | 3.9654 mL | 7.9308 mL | 15.8617 mL |
| 10mM | 0.3965 mL | 1.9827 mL | 3.9654 mL | 7.9308 mL |
| 20mM | 0.1983 mL | 0.9914 mL | 1.9827 mL | 3.9654 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.