Home > Signaling Pathways>Transmembrane>iGluR>Traxoprodil (CP101,606)
Traxoprodil (CP101,606)

This product is for research use only, not for human use. We do not sell to patients.

Traxoprodil (CP101,606)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$850To Be Confirmed
500mg$1350To Be Confirmed
1g$2025To Be Confirmed

Cat #: V5274 CAS #: 134234-12-1 Purity ≥ 98%

Description: Traxoprodil (CP-101606, CP 98113, and CP101,606) is a novel, potent and selective NMDA (NR2B N-Methyl-D-Aspartate) antagonist with neuroprotective effects.

References: Chenard BL, et al. (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses. J Med Chem. 1995 Aug 4; 38(16):3138-45.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)327.42
Molecular FormulaC20H25NO3
CAS No.134234-12-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VivoTraxoprodil is effective in blocking haloperidol-induced stiffness, ED50 Less than 1 mg/kg. Traxoprodil effectively blocks the induction of cfos in NMDA (ip)-stimulated mice at 1 mg/kg
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0542 mL15.2709 mL30.5418 mL61.0836 mL
5mM0.6108 mL3.0542 mL6.1084 mL12.2167 mL
10mM0.3054 mL1.5271 mL3.0542 mL6.1084 mL
20mM0.1527 mL0.7635 mL1.5271 mL3.0542 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.