Tioxolone

This product is for research use only, not for human use. We do not sell to patients.

Tioxolone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$450Check With Us
50g$700Check With Us
100g$1050Check With Us

Cat #: V0896 CAS #: 4991-65-5 Purity ≥ 99%

Description: Tioxolone (Thioxolone) is a potent inhibitor of metalloenzyme carbonic anhydrase I with a variety of activities such as cytostatic, antipsoriatic, anti-acne, antibacterial and anti-mycotic properties.

References: Maryam Hakimi Parizi, et al. Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation. Asian Pacific Journal of Tropical Medicine 2019; 12(8): 365-374.

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Product Promise

Promise
Molecular Weight (MW)168.17
Molecular FormulaC7H4O3S
CAS No.4991-65-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 34 mg/mL (202.2 mM)r
Water: < 1 mg/mLr
Ethanol: 34 mg/mL (202.17 mM)
SMILES CodeO=C1OC2=CC(O)=CC=C2S1
SynonymsTioxolone; Thioxolone;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.9464 mL29.7318 mL59.4636 mL118.9273 mL
5mM1.1893 mL5.9464 mL11.8927 mL23.7855 mL
10mM0.5946 mL2.9732 mL5.9464 mL11.8927 mL
20mM0.2973 mL1.4866 mL2.9732 mL5.9464 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.