This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | 3-6 Days |
| 10mg | $300 | 3-6 Days |
| 25mg | $480 | 3-6 Days |
| 50mg | $740 | 3-6 Days |
| 100mg | $1040 | 3-6 Days |
| 250mg | $1520 | 3-6 Days |
| 500mg | $2140 | 3-6 Days |
: Cat #: V4153 CAS #: 1353644-70-8 Purity ≥ 99%
Description: Theliatinib (formerly HMPL-309; HMPL309; HMPL 309; xiliertinibum; xiliertinib) is a novel and highly potent EGFR-TKI (epidermal growth factor receptor-tyrosine kinase inhibitor) with potential antitumor and anti-angiogenesis activities. It inhibits EGFR with IC50 values of 3 nM and 22 nM against EGFR and EGFR T790M/L858R mutant, and a Ki value of 0.05 nM against EGFR of the wild typ
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 442.512944698334 |
|---|---|
| Molecular Formula | C25H26N6O2 |
| CAS No. | 1353644-70-8 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | Theliatinib; HMPL309; HMPL 309; HMP-L309; xiliertinibum; xiliertinib |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2598 mL | 11.2991 mL | 22.5982 mL | 45.1964 mL |
| 5mM | 0.4520 mL | 2.2598 mL | 4.5196 mL | 9.0393 mL |
| 10mM | 0.2260 mL | 1.1299 mL | 2.2598 mL | 4.5196 mL |
| 20mM | 0.1130 mL | 0.5650 mL | 1.1299 mL | 2.2598 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.