Terbutaline

This product is for research use only, not for human use. We do not sell to patients.

Terbutaline
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$220To Be Confirmed
5g$380To Be Confirmed
10g$570To Be Confirmed

Cat #: V16089 CAS #: 23031-25-6 Purity ≥ 98%

Description: Terbutaline is a potent and selective β2-adrenergic receptor agonist with IC50 of 53 NM, it has little or no effect on alpha-adrenergic receptors.

References: Nada Choucair-Jaafar, et al. The antiallodynic action of nortriptyline and terbutaline is mediated by β(2) adrenoceptors and δ opioid receptors in the ob/ob model of diabetic polyneuropathy. Brain Res. 2014 Feb 10;1546:18-26.

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Product Promise

Promise
Molecular Weight (MW)225.28
Molecular FormulaC12H19NO3
CAS No.23031-25-6
ProtocolIn VivoTerbutaline (intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days) treatment can improve the allodynia in ob/ob mice
Animal modelAdult male ob/ob mice
Dosages0.5 mg/kg
AdministrationIntraperitoneal injection; 0.5 mg/kg; twice a day; 20 days
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4389 mL22.1946 mL44.3892 mL88.7784 mL
5mM0.8878 mL4.4389 mL8.8778 mL17.7557 mL
10mM0.4439 mL2.2195 mL4.4389 mL8.8778 mL
20mM0.2219 mL1.1097 mL2.2195 mL4.4389 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.