Teneligliptin hydrobromide hydrate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$450	To Be Confirmed
500mg	$750	To Be Confirmed
1g	$1125	To Be Confirmed

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Cat #: V32582 CAS #: 1572583-29-9 Purity ≥ 99%

Description: Teneligliptin HBr hydrate (formerly MP513; MP-513; trade name Tenelia in Japan), the hydrobromide salt and hydrated form of Teneligliptin, is an orally bioavailable and long-lasting dipeptidyl peptidase-4 (DPP-4) inhibitor approved for the treatment of type 2 diabetes mellitus in Japan.

References: Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.

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Molecular Weight (MW)	426.58
Molecular Formula	C22H30N6OS
CAS No.	1572583-29-9
Synonyms	Teneligliptin hydrobromide hydrate

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3442 mL	11.7211 mL	23.4423 mL	46.8845 mL
5mM	0.4688 mL	2.3442 mL	4.6885 mL	9.3769 mL
10mM	0.2344 mL	1.1721 mL	2.3442 mL	4.6885 mL
20mM	0.1172 mL	0.5861 mL	1.1721 mL	2.3442 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.