Tecovirimat hydrate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

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500mg	Get quote
1g	Get quote

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Cat #: V3887 CAS #: 1162664-19-8 Purity ≥ 98%

Description: Tecovirimat hydrate (formerly ST246; SIGA246; ST-246; SIGA-246; POXX), the hydrated form of Tecovirimat which is a p37 envelope protein inhibitor, is a small synthetic antiviral drug approvd on 7/13/2018 for the treatment of smallbox infection.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	394.35
Molecular Formula	C19H17F3N2O4
CAS No.	1162664-19-8
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 10mM
	Water: N/A
	Ethanol: N/A
SMILES Code	O=C(NN(C(C1C2C(C3)C3C(C=C2)C41)=O)C4=O)C5=CC=C(C(F)(F)F)C=C5.[H]O[H]
Synonyms	ST-246 hydrate; ST 246; ST246; SIGA-246; SIGA246; SIGA 246 hydrate;

Related Biological Data

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5358 mL	12.6791 mL	25.3582 mL	50.7164 mL
5mM	0.5072 mL	2.5358 mL	5.0716 mL	10.1433 mL
10mM	0.2536 mL	1.2679 mL	2.5358 mL	5.0716 mL
20mM	0.1268 mL	0.6340 mL	1.2679 mL	2.5358 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.