TCS-OX2-29 HCl

This product is for research use only, not for human use. We do not sell to patients.

TCS-OX2-29 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1080Check With Us
500mg$1550Check With Us
1g$2325Check With Us

Cat #: V3411 CAS #: 1610882-30-8 Purity ≥ 98%

Description: TCS-OX2-29 HCl, the hydrochloride salt of TCS-OX229, is a non-peptide and selective OX2 receptor antagonist (IC50 = 40 nM) with potential use in the treatment of insomnia.

References: Hirose M, et al. N-acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: the first orexin-2 receptor selective non-peptidic antagonist. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4497-9. 

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)433.98
Molecular FormulaC23H32ClN3O3
CAS No.1610882-30-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mM in DMSOr
Water: NAr
Ethanol: NA
SMILES CodeCC(C)(C)[C@H](NCC1=CC=NC=C1)C(N2CC3=C(C=C(OC)C(OC)=C3)CC2)=O.[H]Cl
SynonymsTCSOX 229 HCl, TCSOX229 hydrochloride, TCSOX 229 hydrochloride, TCS OX229, TCS-OX2-29, TCS OX-229, TCS-OX229, TCS OX2 29, TCS OX2 29, TCS OX2 29 hydrochloride
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3043 mL11.5213 mL23.0425 mL46.0851 mL
5mM0.4609 mL2.3043 mL4.6085 mL9.2170 mL
10mM0.2304 mL1.1521 mL2.3043 mL4.6085 mL
20mM0.1152 mL0.5761 mL1.1521 mL2.3043 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.