Taltirelin (TA0910)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$1150	Check With Us
500mg	$1750	Check With Us
1g	$2625	Check With Us

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Cat #: V15711 CAS #: 103300-74-9 Purity ≥ 98%

Description: Taltirelin (TA-0910; tradename Ceredist) is a thyrotropin-releasing hormone (TRH) analog and a TRH mimic that acts as a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release).

References: Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	405.41
Molecular Formula	C17H23N7O5
CAS No.	103300-74-9
SMILES Code	O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC(N3C)=O)NC3=O)=O)=O)CCC1
Synonyms	Taltirelin; TA 0910; TA-0910; TA0910; CCRIS 8513;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.4666 mL	12.3332 mL	24.6664 mL	49.3328 mL
5mM	0.4933 mL	2.4666 mL	4.9333 mL	9.8666 mL
10mM	0.2467 mL	1.2333 mL	2.4666 mL	4.9333 mL
20mM	0.1233 mL	0.6167 mL	1.2333 mL	2.4666 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.