Home > Signaling Pathways>Vitamin D Related/Nuclear Receptor>VD/VDR>Tacalcitol [1,24(R)-Dihydroxyvitamin D3]
Tacalcitol [1,24(R)-Dihydroxyvitamin D3]

This product is for research use only, not for human use. We do not sell to patients.

Tacalcitol [1,24(R)-Dihydroxyvitamin D3]
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$4875To Be Confirmed
200mg$7312To Be Confirmed
500mg$12340To Be Confirmed

Cat #: V5290 CAS #: 57333-96-7 (free) Purity ≥ 98%

Description: Tacalcitol [1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3] is a vitamin D3 analog (isomer of Vitamin D3) that promotes normal bone development by regulating calcium.

References: Masuo Morisaki , aoyuki Koizumi , Nobuo Ikekawa et al. Synthesis of active forms of vitamin D. Part IX. Synthesis of 1α,24-dihydroxycholecalciferol. J. Chem. Soc., Perkin Trans. 1, 1975, 1421-1424

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Product Promise

Promise
Molecular Weight (MW)416.64
Molecular FormulaC27H44O3
CAS No.57333-96-7 (free)
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeC=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2[C@H]3[C@]([C@@H]([C@H](C)CC[C@@H](O)C(C)C)CC3)(C)CCC/2
SynonymsTacalcitol; Bonalfa; Curatoderm; TV 02; TV-02; TV02; PRI 2191; PRI-2191; PRI2191;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4002 mL12.0008 mL24.0015 mL48.0031 mL
5mM0.4800 mL2.4002 mL4.8003 mL9.6006 mL
10mM0.2400 mL1.2001 mL2.4002 mL4.8003 mL
20mM0.1200 mL0.6000 mL1.2001 mL2.4002 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.