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| Size | Price | Stock |
|---|---|---|
| 10mg | $850 | 3-6 Days |
| 25mg | $1390 | 3-6 Days |
| 50mg | $2110 | 3-6 Days |
| 100mg | $3160 | 3-6 Days |
| 250mg | $5360 | 3-6 Days |
: Cat #: V15635 CAS #: 2437475-16-4 Purity ≥ 99%
Description: T6167923 (T-6167923) is a novel and potent inhibitor of MyD88-dependent signaling pathways with anti-inflammatory activity. It acts by binding to Toll/IL1 receptor (TIR) domain of MyD88 and disrupting the formation of MyD88 homodimer. T6167923 inhibits pro-inflammatory cytocines with IC50s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively.
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| Molecular Weight (MW) | 458.393 |
|---|---|
| Molecular Formula | C17N3O3S2BRH20 |
| CAS No. | 2437475-16-4 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1815 mL | 10.9077 mL | 21.8153 mL | 43.6307 mL |
| 5mM | 0.4363 mL | 2.1815 mL | 4.3631 mL | 8.7261 mL |
| 10mM | 0.2182 mL | 1.0908 mL | 2.1815 mL | 4.3631 mL |
| 20mM | 0.1091 mL | 0.5454 mL | 1.0908 mL | 2.1815 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.