Sulmazole

This product is for research use only, not for human use. We do not sell to patients.

Sulmazole
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$330To Be Confirmed
250mg$600To Be Confirmed
500mg$900To Be Confirmed

Cat #: V15521 CAS #: 73384-60-8 Purity ≥ 99%

Description: Sulmazole (Vardax; AR-L 115BS; AR-L 115-BS) is an A1 adenosine receptor antagonist that inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.

References: W J Parsons, et al. The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi. Mol Pharmacol. 1988 Apr;33(4):441-8.

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Molecular Weight (MW)287.34
Molecular FormulaC14H13N3O2S
CAS No.73384-60-8
ProtocolIn VitroSulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4802 mL17.4010 mL34.8020 mL69.6040 mL
5mM0.6960 mL3.4802 mL6.9604 mL13.9208 mL
10mM0.3480 mL1.7401 mL3.4802 mL6.9604 mL
20mM0.1740 mL0.8700 mL1.7401 mL3.4802 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.