This product is for research use only, not for human use. We do not sell to patients.
Size | Price | Stock |
---|---|---|
100mg | $1150 | Check With Us |
200mg | $1725 | Check With Us |
500mg | $2910 | Check With Us |
Cat #: V60029 CAS #: 1212012-37-7 Purity ≥ 99%
Description: Sulfosuccinimidyl oleate sodium (SSO sodium salt) is a long chain fatty acid acting as an irreversible inhibitor of the fatty acid translocase CD36, blocking uptake of oleate, linoleate, or stearate by about 65% when added at 200 µM to adipocytes.
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 481.58 |
---|---|
Molecular Formula | C22H36NNaO7S |
CAS No. | 1212012-37-7 |
SMILES Code | CCCCCCCC/C=C\CCCCCCCC(ON1C(C(S(O)(=O)=O)CC1=O)=O)=O.[Na+] |
Synonyms | Sulfosuccinimidyl oleate sodium; Sulfo-N-succinimidyl oleate sodium |
Protocol | In Vitro | Sulfosuccinimidyl oleate (50 μM, 24 hours) co-treatment significantly reduces the LPS+IFNγ-induced expression of NOS2 and COX-2 in BV2 cells. Western blot analysis reveals a significant LPS/IFNγ-induced upregulation in the phosphorylated form of the p38, which is prevented by co-treatment with Sulfosuccinimidyl oleate (50 μM, 24 hours). Sulfosuccinimidyl oleate (20 μM and 50 μM, 24 hours) alone does not alter the cellular viability. Exposure to 100 ng/ml LPS+5 ng/mL IFNγ modestly, yet significantly reduces the viability of the BV2 cells. Co-treatment with Sulfosuccinimidyl oleate prevents the LPS+IFNγ-induced reduction in the cell viability. |
---|---|---|
In Vivo | Sulfosuccinimidyl oleate (50 mg/kg; administered once by single oral gavage) significantly reduces the cortical ischemic infarct size compared to vehicle-treated controls in male BALB/cABom mice with pMCAo model. In addition, Sulfosuccinimidyl oleate at 50 mg/kg is suitable to see a beneficial effect after stroke. |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.0765 mL | 10.3825 mL | 20.7650 mL | 41.5300 mL |
5mM | 0.4153 mL | 2.0765 mL | 4.1530 mL | 8.3060 mL |
10mM | 0.2076 mL | 1.0382 mL | 2.0765 mL | 4.1530 mL |
20mM | 0.1038 mL | 0.5191 mL | 1.0382 mL | 2.0765 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.