Sudoterb (LL3858)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25mg	$380	To Be Confirmed
50mg	$550	To Be Confirmed
100mg	$900	To Be Confirmed
250mg	$1650	To Be Confirmed

: [email protected] [email protected]

Cat #: V2056 CAS #: 676266-31-2 Purity ≥ 98%

Description: Sudoterb (formerly also known as LL3858; LL-3858) is a novel and potent drug candidate with the potential for treating Tuberculosis (TB). TB drug research and development efforts have resurged in the past 10 years to meet urgent medical needs, but enormous challenges remain. These urgent needs are largely driven by the current long and arduous multidrug regimens, which have significant safety, tolerability and compliance issues; rising and disturbing rates of multidrug- and extensively drug-resistant TB; the existence of approximately 2 billion individuals already latently infected with Mycobacterium tuberculosis, the causative pathogen of TB; and a global TB-HIV co-epidemic.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	519.57
Molecular Formula	C29H28F3N5O
CAS No.	676266-31-2
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: ≥ mg/mL
	Water: N/A
	Ethanol: N/A
SMILES Code	O=C(C1=CC=NC=C1)NN2C(C)=C(CN3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)C=C2C5=CC=CC=C5
Synonyms	LL-3858; LL3858; LL 3858

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9247 mL	9.6233 mL	19.2467 mL	38.4934 mL
5mM	0.3849 mL	1.9247 mL	3.8493 mL	7.6987 mL
10mM	0.1925 mL	0.9623 mL	1.9247 mL	3.8493 mL
20mM	0.0962 mL	0.4812 mL	0.9623 mL	1.9247 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.