SU5607
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | Check With Us |
| 500mg | $1450 | Check With Us |
| 1g | $2175 | Check With Us |
: Cat #: V12863 CAS #: 186611-52-9 Purity ≥ 99%
Description: SU5607 is a novel and potent CK1 inhibitor.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 311.33 |
|---|---|
| Molecular Formula | C18H17NO4 |
| CAS No. | 186611-52-9 |
| SMILES Code | COC1=C(/C=C2C(NC3=C/2C=CC=C3)=O)C(OC)=CC(OC)=C1 |
| Synonyms | IC261; IC-261; IC 261 SU5607; SU-5607; SU 5607 |
| Protocol | In Vitro | IC261 is a selective, ATP-competitive CK1 inhibitor, with IC50s of 1 μM, 1 μM, 16 μM for Ckiδ, Ckiε and Ckiα1, respectively. IC261 is less active on PKA, p34cdc2, and p55fyn (IC50s > 100 μM). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.2120 mL | 16.0601 mL | 32.1203 mL | 64.2405 mL |
| 5mM | 0.6424 mL | 3.2120 mL | 6.4241 mL | 12.8481 mL |
| 10mM | 0.3212 mL | 1.6060 mL | 3.2120 mL | 6.4241 mL |
| 20mM | 0.1606 mL | 0.8030 mL | 1.6060 mL | 3.2120 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.