STF-118804

This product is for research use only, not for human use. We do not sell to patients.

STF-118804
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$930Check With Us
500mg$1450Check With Us
1g$2175Check With Us

Cat #: V3033 CAS #: 894187-61-2 Purity ≥ 98%

Description: STF-118804 is a highly specific and potent inhibitor of NAMPT (nicotinamide phosphoribosyl transferase) with IC50 values in the low nanomolar range.

References: Matheny CJ, et al. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21;20(11):1352-63.

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Product Promise

Promise
Molecular Weight (MW)461.53
Molecular FormulaC25H23N3O4S
CAS No.894187-61-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 61 mg/mL (132.16 mM)r
Water: <1 mg/mLr
Ethanol:
SMILES CodeO=C(NCC1=CC=CN=C1)C2=CC=C(C3=NC(CS(=O)(C4=CC=C(C)C=C4)=O)=C(C)O3)C=C2
SynonymsSTF 118804; STF118804; STF-118804
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1667 mL10.8335 mL21.6671 mL43.3341 mL
5mM0.4333 mL2.1667 mL4.3334 mL8.6668 mL
10mM0.2167 mL1.0834 mL2.1667 mL4.3334 mL
20mM0.1083 mL0.5417 mL1.0834 mL2.1667 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.