STF-083010

This product is for research use only, not for human use. We do not sell to patients.

STF-083010
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$850Check With Us
500mg$1350Check With Us
1g$2025Check With Us

Cat #: V1900 CAS #: 307543-71-1 Purity ≥ 98%

Description: STF-083010 (formerly IRE1 Inhibitor I) is a novel and specific small-molecule inhibitor of IRE1α endonuclease.

References: Papandreou I, et al. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood. 2011 Jan 27;117(4):1311-4.

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Product Promise

Promise
Molecular Weight (MW)317.38
Molecular FormulaC15H11NO3S2
CAS No.307543-71-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 63 mg/mL (198.5 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=S(C1=CC=CS1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
SynonymsIRE1 Inhibitor I; STF-083010; STF 083010; STF083010
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1508 mL15.7540 mL31.5080 mL63.0159 mL
5mM0.6302 mL3.1508 mL6.3016 mL12.6032 mL
10mM0.3151 mL1.5754 mL3.1508 mL6.3016 mL
20mM0.1575 mL0.7877 mL1.5754 mL3.1508 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.