SR3335

This product is for research use only, not for human use. We do not sell to patients.

SR3335
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1160Check With Us
500mg$1750Check With Us
1g$2625Check With Us

Cat #: V4025 CAS #: 293753-05-6 Purity ≥ 98%

Description: SR3335 (also known as ML-176) is a novel and selective RORα inverse agonist with a Ki of 220 nM.

References: Kumar N, et al. Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist. ACS Chem Biol. 2011 Mar 18;6(3):218-22.

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Product Promise

Promise
Molecular Weight (MW)405.33
Molecular FormulaC13H9F6NO3S2
CAS No.293753-05-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 100mg/mLr
Water: N/Ar
Ethanol: N/A
SMILES CodeO=S(C1=CC=CS1)(NC2=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C2)=O
SynonymsSR3335; SR-3335; SR 3335; ML 176; ML-176; ML176.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4671 mL12.3356 mL24.6713 mL49.3425 mL
5mM0.4934 mL2.4671 mL4.9343 mL9.8685 mL
10mM0.2467 mL1.2336 mL2.4671 mL4.9343 mL
20mM0.1234 mL0.6168 mL1.2336 mL2.4671 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.