SR-11302
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | Check With Us |
| 200mg | $1275 | Check With Us |
| 500mg | $1910 | Check With Us |
: Cat #: V41511 CAS #: 160162-42-5 Purity ≥ 99%
Description: SR-11302 (SR11302) is an AP-1 (activator protein-1) transcription factor inhibitor with antitumor activity.
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- Related Biological Data
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| Molecular Weight (MW) | 376.53 |
|---|---|
| Molecular Formula | C26H32O2 |
| CAS No. | 160162-42-5 |
| Synonyms | SR 11302 |
| Protocol | In Vitro | SR 11302 (SR11302) show strong anti-AP-1 activity with selective binding with RARα and RARγ, but not with RARβ and RXRα. |
|---|---|---|
| In Vivo | SR 11302 (SR11302; low dose 0.5 mg/kg and high dose 1 mg/kg body weight; orally gavaged daily) treatment reduces the total vascular lesion number and lesion size in Vldlr-/- mice in a dose-dependent manner. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6558 mL | 13.2792 mL | 26.5583 mL | 53.1166 mL |
| 5mM | 0.5312 mL | 2.6558 mL | 5.3117 mL | 10.6233 mL |
| 10mM | 0.2656 mL | 1.3279 mL | 2.6558 mL | 5.3117 mL |
| 20mM | 0.1328 mL | 0.6640 mL | 1.3279 mL | 2.6558 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.