Solriamfetol HCl

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V15047 CAS #: 178429-62-4 Purity ≥ 99%

Description: Solriamfetol HCl (YKP-10A; ADXN-05; R228060; SKL-N-05; JZP-11; Sunosi), the hydrochloride salt of Solriamfetol which is a wake-promoting agent, is a norepinephrine–dopamine inhibitor that was approved in 2019 for the treatment of excessive sleepiness associated with narcolepsy and sleep apnea.

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Molecular Weight (MW)	230.692
Molecular Formula	C10H15ClN2O2
CAS No.	178429-62-4
Synonyms	YKP-10A; ADXN-05; R228060; SKL-N-05; JZP-11

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.3348 mL	21.6739 mL	43.3478 mL	86.6957 mL
5mM	0.8670 mL	4.3348 mL	8.6696 mL	17.3391 mL
10mM	0.4335 mL	2.1674 mL	4.3348 mL	8.6696 mL
20mM	0.2167 mL	1.0837 mL	2.1674 mL	4.3348 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.