Sodium Tauroursodeoxycholate (TUDC)

This product is for research use only, not for human use. We do not sell to patients.

Sodium Tauroursodeoxycholate (TUDC)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$803-6 Days
500mg$1003-6 Days
1g$1403-6 Days
2g$1803-6 Days

Cat #: V1890 CAS #: 35807-85-3 Purity ≥ 99%

Description: Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, which is used for the treatment of gallstones and liver cirrhosis. Tauroursodeoxycholate exhibits protective and reversing effects in vitro against the impairment of the cVA-of-CLF brought on by 17βEG. Tauroursodeoxycholate reduces cell growth in Mz-ChA-1 cholangiocarcinoma cells through pathways that depend on Ca2+-, PKC, and MAPK. Tauroursodeoxycholate inhibits bile acid-induced apoptosis in isolated rat hepatocytes by causing the formation of cAMP through the β1-integrin.

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Molecular Weight (MW)521.69
Molecular FormulaC26H44NNaO6S
CAS No.35807-85-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsTUDCA sodium; ; Sodium tauroursodeoxycholate; Tauroursodeoxycholic acid sodium salt
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9168 mL9.5842 mL19.1685 mL38.3369 mL
5mM0.3834 mL1.9168 mL3.8337 mL7.6674 mL
10mM0.1917 mL0.9584 mL1.9168 mL3.8337 mL
20mM0.0958 mL0.4792 mL0.9584 mL1.9168 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.