SIRT6 activator 12q

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5mg	$100	To Be Confirmed
10mg	$170	To Be Confirmed
50mg	$500	To Be Confirmed
100mg	$760	To Be Confirmed

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Cat #: V36332 CAS #: 2601734-99-8 Purity ≥ 99%

Description: SIRT6 activator 12q is a specific and orally bioactive SIRT6 activator with IC50s of 171.20, >200, >200, >200 and 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5 and SIRT6 respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q causes apoptosis (Apoptosis) and cell cycle arrest in the G2 phase. SIRT6 activator 12q displays anti-cancer activity.

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Molecular Weight (MW)	454.518587589264
Molecular Formula	C31H22N2O2
CAS No.	2601734-99-8
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2001 mL	11.0007 mL	22.0013 mL	44.0026 mL
5mM	0.4400 mL	2.2001 mL	4.4003 mL	8.8005 mL
10mM	0.2200 mL	1.1001 mL	2.2001 mL	4.4003 mL
20mM	0.1100 mL	0.5500 mL	1.1001 mL	2.2001 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.