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SGC2085 HCl

This product is for research use only, not for human use. We do not sell to patients.

SGC2085 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$845Check With Us
500mg$1350Check With Us
1g$2025Check With Us
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Cat #: V2107 CAS #: 1821908-49-9 Purity ≥ 98%

Description: SGC2085 HCl, identified from virtual screening approaches, is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM.

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Molecular Weight (MW)348.87
Molecular FormulaC19H25ClN2O2
CAS No.1821908-49-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: >62 mg/mL (198.45 mM)r
Water: <1 mg/mLr
Ethanol: 62 mg/mL (198.45 mM)
SMILES CodeC[C@H](N)C(NCC1=CC=C(OC2=CC(C)=CC(C)=C2)C(C)=C1)=O.[H]Cl
SynonymsSGC2085 HCl; SGC-2085 hydrochloride; SGC 2085
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8664 mL14.3320 mL28.6640 mL57.3279 mL
5mM0.5733 mL2.8664 mL5.7328 mL11.4656 mL
10mM0.2866 mL1.4332 mL2.8664 mL5.7328 mL
20mM0.1433 mL0.7166 mL1.4332 mL2.8664 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.